The pathogenesis of pancreatic cancer involves substantial metabolic reprogramming, resulting in abnormal proliferation of tumor cells.This tumorigenic reprogramming is often driven by genetic mutations, such as activating mutations of the KRAS oncogene and inactivating or deletions of the tumor suppressor genes SMAD4, CDKN2A, and TP53, which play

Scrub typhus is a leading cause of febrile illness in endemic countries due to infection with Orientia tsutsugamushi (Ot), a seriously understudied intracellular bacterium.Pulmonary involvement associated with vascular parasitism in patients is common and can develop into life threatening interstitial pneumonia.The diverse antigenicity of Ot genoty

Klebsiella pneumoniae is an important pathogen that can infect both humans and cattle.The widespread K.pneumoniae and its high drug resistance make it difficult to treat Klebsiella infections/diseases.In this study, a lytic K.pneumoniae bacteriophage vB_Kpn_B01 was isolated from a dairy farm trough in Sichuan Province, and its Intimate Wash biologi

Using the framework of semiclassical Landau-Lifshitz dynamics (LLD), we conduct a systematic investigation of the temperature-dependent spin dynamics in the S=1/2 Heisenberg square-lattice antiferromagnet (SAFM).By performing inelastic neutron scattering measurements on Zn_{2}VO(PO_{4})_{2} (ZVPO) and corresponding finite-temperature spin dynamics

The article studies the process of analogue organization changing at the expense of introducing artificial intellect technologies.In the development of organization management technologies we can distinguish three stages of their evolution: automation, informatization and digitalization.Automation was used in the period of functional management tha